Rendell and Whitehead adopt a weak definition of culture to allow low standards of evidence for marine mammals, but they do not adequately rule out genetic factors or individual versus social learning. They then use these low standards to argue that some whales have unique cultures only matched by humans. It would have been more helpful to specify data gaps and suggest critical tests.

The study of intellectual humility is still in its early stages and issues of definition and measurement are only now being explored. To inform and guide the process of defining and measuring this important intellectual virtue, we conducted a series of studies into the implicit theory – or ‘folk’ understanding – of an intellectually humble person, a wise person, and an intellectually arrogant person. In Study 1, 350 adults used a free-listing procedure to generate a list of descriptors, one for (...) each person-concept. In Study 2, 335 adults rated the previously generated descriptors by how characteristic each was of the target person-concept. In Study 3, 344 adults sorted the descriptors by similarity for each person-concept. By comparing and contrasting the three person-concepts, a complex portrait of an intellectually humble person emerges with particular epistemic, self-oriented, and other-oriented dimensions. (shrink)

The many gods of modernity -- The dynamics of relativization -- Relativism -- Fundamentalism -- Certainty and doubt -- The limits of doubt -- The politics of moderation.

This book emphasizes that analysis of broad economic changes treats people abstractly, while a personalist view sees them as human agents who, while needing and generating economic goods, must still be responsive to others and be aware of values and goals beyond temporal well-being. Visit our website for sample chapters!

D. W. Winnicott is increasingly recognized as one of the most important psychoanalysts since Freud, but the relevance of his Independent version of object relations theory to psychoanalytic literary criticism has not been sufficiently appreciated. As Peter L. Rudnytsky notes, "There must be ten literary critics conversant with Lacan's ecrits for every one who has read Winnicott's Playing and Reality." Transitional Objects and Potential Spaces begins to redress this imbalance. The title and subtitle of this collection highlight three of (...) Winnicott's key concepts: transitional objects, potential space, and the use of an object. Because Winnicott is unique in respecting the integrity of art as an autonomous human activity while continuing to insist on its infantile origins, he may be said to offer the first adequate psychoanalytic account of aesthetics. This volume is organized into three sections: The Analytic Frame, Literary Objects, and Cultural Fields. Beginning with Winnicott's "The Location of Cultural Experience," it features essays by a distinguished group of contributors, including Marion Milner and two current leading members of the British Psycho-Analytical Society, Christopher Bollas and Patrick J. Casement, as well as such eminent critics as Richard Poirier, Murray M. Schwartz, Ellen Handler Spitz, and Madelon Sprengnether. Transitional Objects and Potential Spaces makes a timely and persuasive case for the power of Winnicott's ideas. In defining for the first time an independent tradition of psychoanalytic criticism, it will reorient future work in literary and cultural studies. (shrink)

Participants of low and high hypnotic susceptibility were tested on a temporal order judgement task, both with and without hypnosis. Judgements were made of the order of presentation of light flashes appearing in first one hemi-field then the other. There were differences in the inter-stimulus intervals required accurately to report the order, depending upon which hemi-field led. This asymmetry was most marked in hypnotically susceptible participants and reversed when they were hypnotised. This implies not only that brain activity changes in (...) hypnosis, but also that there is a difference in brain function between people of low and high hypnotic susceptibility. The latter exhibited a faster-acting left hemisphere in the waking state, but faster right when hypnotised. (shrink)

I contend that s. Haack's proposed definition of fallibilism is unsatisfactory being equivalent to the assertion that we can believe anything. I say that fallibilism is best conceived as the doctrine that all our theories are false.

It has been maintained that we are quite able to express (1*)–(4*) without the introduction of a dyadic deontic operator, provided only that we supply our standard deontic logic with a stronger conditional than material implication. The lesson learned from Chisholm's paradox has been the eminently convincing, indeed obvious, one: that what we ought to do is not determined by what is the case in some perfect world, but by what is the case in the best world we can ‘get (...) to’ from this world. What we ought to do depends upon how we are circumstanced. (shrink)

Pope John Paul II's opposition to the Iraq War was not that it failed to meet the conditions of Just War Theory. Indeed, we cannot tell from what he publicly said whether he thought it met those conditions or not, for he would have opposed it in any case. His thinking was rather that even just and necessary wars always come, as it were, too late, and are never able to solve the problems that made wars just and necessary. He (...) was not trying therefore to enter into the details of Just War Theory. He wanted to subsume the principles of war into the principles of peace and to do so, not by denying justice, but by transcending it with charity. This article shows how this thinking is to be understood and the many means the Pope devised for putting this thinking into practice. (shrink)

Mucins are a family of high molecular weight, highly glycosylated glycoproteins found in the apical cell membrane of human epithelial cells from the mammary gland, salivary gland, digestive tract, respiratory tract, kidney, bladder, prostate, uterus and rete testis. Increased synthesis of the core protein and alterations in the carbohydrates attached to these glycoproteins are believed to play important roles in the function and proliferation of tumour cells. Aberrant glycosylation leads not only to the production of novel carbohydrate structures, but also (...) to the exposure of the core peptide. These novel epitopes may be candidates for diagnosis or therapy, by using either synthetic mucin fragments as vaccines, or monoclonal antibody‐based reagents which detect these structures. (shrink)

Oxygenated derivatives of cholesterol (oxysterols) are widely distributed in nature, being found in the blood and tissues of animals and man as well as in foodstuff. They exhibit many biological activities which are of potential physiological, pathological or pharmacological importance. Many oxysterols have been found to be potent inhibitors of cholesterol biosynthesis and one or more oxysterols may play a role as the physiologic feedback regulator of cholesterol synthesis. Oxysterols also inhibit cell replication and have cytotoxic properties effects which suggest (...) that these sterols may participate in the regulation of cell proliferation and may be potentially useful as therapeutic agents for cancer. Furthermore, there is considerable evidence that oxysterols may be involved in the pathogenesis of atherosclerosis. Although the mechanism of action of oxysterols in all these instances is not well understood, the existence of cytosolic and microsomal proteins which bind oxysterols with high affinity and specificity suggests that this group of compounds may represent a family of intracellular regulatory molecules. (shrink)

No descriptive material is available for this title.

ABSTRACT:In this paper we examine how ethical values contribute to national economic prosperity. We extend the concept of an ethical wealth of nations first introduced by Donaldson in which he proposed four categories of ethical values—fairer distribution of goods, better government, ingrained social cooperation, and inculcation of economic duties—that can drive economic performance, but only if citizens ascribe “intrinsic value” to them independent of their economic interests. Our analysis draws on institutional economics and sociology research to show that if ethical (...) values are to drive economic performance, they must also be supported by the institutional fabric of the nation. We embed an expanded set of ethical values in a set of democratic, free market and civil society institutions spanning three sectors of society—political, economic and cultural respectively. We conclude by discussing the implications of our institutional framework for moral education. (shrink)

‚Quer‘ is the keyword for our new effort to interpret ‚der ganze Fichte‘. The first part of our contribution presents Johann Gottlieb Fichte as a rebellious philosopher of strong subjectivity. With his prominent figures of the i, the nation and the savant (Gelehrter), he also stands crosswise (quer) against his own contemporary time, the history of his reception and our contemporary time. The second part of this study considers Fichtes theory of death as a counterpart of the usual interpretation of (...) the Wissenschaftslehre as a theory of life. Different manifestation of death – from physical death to the death of the Wissenschaftslehre – are systematically analyzed. ‚Quer‘ bildet das Stichwort für unseren Versuch, den ‚ganzen Fichte‘ auf eine neue Art und Weise zu deuten. Der erste Teil unseres Beitrages exponiert Johann Gottlieb Fichte als rebellischen Denker starker Subjektivität. Mit seinen prominenten Gedankenfiguren des Ich, der Nation und des philosophischen Gelehrten steht er demnach sowohl ‚quer‘ gegen seine Zeit, als auch gegen seine Rezeptionsgeschichte sowie gegen unsere zeitgenössische Gegenwart. Im zweiten Teil wird gegen die rezeptionsgeschichtlich dominante Lebenslehre Fichtes deren antithetischer Gegenspieler, der Tod, in den Blick genommen. Hier wird versucht, Fichtes Verständnis des Todes und dessen Erscheinungsformen – vom physischen Tod bis zum Tod der Wissenschaftslehre – in einem systematischen Ansatz zu durchdenken. (shrink)

The text of Aristotle'sEthica Eudemia is often in need of emendation, especially because of the particular fault in the manuscripts of misreading one letter for another or misdividing letters to form words. Scholars have already done fine work in correcting many of these errors, but more needs to be done. A second problem with the text does not have to do with matters of spelling or grammar, but rather with those of philosophical sense. For, as scholars have noted, theEEis marked (...) by considerable compression of thought, and this compression leads scholars to propose changes where, on further consideration, it can be shown that not change of words but change of comprehension is needed. (shrink)

Among the works on ethics in the Aristotelian corpus, there is no serious dispute among scholars that the "Eudemian Ethics "is authentic. The "Eudemian Ethics "is" "increasingly read and used by scholars as a useful support and confirmation and sometimes contrast to the "Nicomachean Ethics." Yet, it remains a largely neglected work in the study of Aristotle's ethics, both among scholars and moral philosophers. Peter L. P. Simpson provides an analytical outline of the entire work together with summaries of (...) each individual section, making the overall structure and detailed argument clear. His translation and explanatory notes include the common books that the "Eudemian" "Ethics" shares with the "Nicomachean." This translation contains renderings of words and phrases, and proposals for emending the text that differ from what other translators and scholars have adopted. This translation is literal, without expansion or paraphrase, and yet also readable. A readable but literal translation is necessary because in the "Eudemian Ethics," more than usual in Aristotle's writings, the logic of the argumentation can turn on the peculiar wording or order. Simpson explains the argumentation where necessary in notes and separate explanatory comments. This book is a fresh, twenty-first-century rendition of the work of one of the most eminent philosophers of all time. (shrink)

Actin performs structural as well as motor‐like functions in eukaryotic cells. Orthologues of actin have also been identified in bacteria, where they perform an essential function during cell growth. Bacterial actins are implicated in the maintenance of rod‐shaped cell morphology, and appear to form a cytoskeletal structure, localising as helical filaments underneath the cell membrane. Recently, a plasmid‐borne actin orthologue has been shown to perform a mitotic‐like function during segregation of a plasmid, and chromosomally encoded actin proteins were found to (...) play an important role in chromosome segregation. Based on the findings that actin filaments are dynamic structures in two bacterial species, we propose that actins perform motor functions rather than a purely structural role in bacteria. We suggest that an intracellular motor exists in bacteria that could be derived from an ancestral actin motor that was present in cells early in evolution. BioEssays 26:1209–1216, 2004. © 2004 Wiley Periodicals, Inc. (shrink)

Aristotle's Ethica Eudemia and Ethica Nicomachea, as is well known and much discussed, contain three books in common. Less well known, at least until Dieter Harlfinger alerted scholars to the fact in 1971, is that some of the manuscripts of Eth. Eud. do, contrary to the then prevailing consensus, contain the text of these common books. Even less well known is that Harlfinger's discovery was anticipated some 50 years before by Walter Ashburner, who had uncovered this fact about Eth. Eud. (...) MSS in the Laurentian library of Florence. Ashburner's anticipation of Harlfinger, however, is not the real value of his article. Its value rather is that it contains collations of readings for the common books, and thereby gives us an excellent resource for examining the text of the common books as this text is contained in exclusively Eth. Eud. MSS. The Eth. Eud. tradition of the common books has hitherto received little attention. Modern editions of Eth. Eud. do not include these books, and editions of Eth. Nic. have other MSS for the purpose. Ashburner's collations are the more valuable because they are taken from the one MS that, in Harlfinger's learned stemma, appears as the archetype for all the rest. (shrink)